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What makes MUC1 a tumor antigen?

Item Type:Article
Title:What makes MUC1 a tumor antigen?
Creators Name:Karsten, U. and von Mensdorff-Pouilly, S. and Goletz, S.
Abstract:The epithelial mucin 1 (MUC1) is an accepted serum tumor marker and cellular tumor antigen. We discuss recent views on the difference(s) between normal and tumor MUC1, and its implication for the development of cancer vaccines and antibody therapies, with special emphasis on the role of glycosylation.
Keywords:Antibody, Conformation, Epithelial Mucin 1, Glycosylation, Immunotherapy, MUC1, Tumor Epitope, Tumor Vaccine, Animals
Source:Tumor Biology
ISSN:1010-4283
Publisher:Karger (Switzerland)
Volume:26
Number:4
Page Range:217-220
Date:6 July 2005
Official Publication:https://doi.org/10.1159/000086956
PubMed:View item in PubMed

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