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Baroreflex Failure

Item Type:Article
Title:Baroreflex Failure
Creators Name:Heusser, K. and Tank, J. and Luft, F.C. and Jordan, J.
Abstract:The baroreflex receives less attention nowadays because most students of hypertension are convinced that faulty volume regulation by the kidneys is responsible for long-term blood pressure increases. However, unusual patients with bilateral destruction of the normal blood pressure–sensing mechanisms can develop profound chronic hypertension. We present 2 patients with baroreflex failure. Both had volatile hypertension with systolic readings up to 300 mm Hg documented over years. Both had muscle sympathetic nerve activity that was increased even while resting. Treating these patients was a stochastic challenge. The therapy is frequently based on medicines that are no longer commonly prescribed.
Keywords:Baroreflex, Sympathetic nervous system, Autonomic nervous system, Hypotension, Bradycardia
Source:Hypertension
ISSN:0194-911X
Publisher:American Heart Association (U.S.A.)
Volume:45
Page Range:834-839
Date:1 January 2005
Official Publication:https://doi.org/10.1161/01.HYP.0000160355.93303.72
PubMed:View item in PubMed

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