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San1p, checking up on nuclear proteins

Item Type:Editorial
Title:San1p, checking up on nuclear proteins
Creators Name:Sommer, T. and Hirsch, C.
Abstract:Cellular quality control mechanisms perform vital tasks by ensuring that the proteome reflects precisely the information encoded by the genome. In this issue of Cell, Gardner et al. (2005) report the discovery of a novel protein quality control system that resides in the nucleus. Central to this system is the E3 ligase San1p, which monitors nuclear proteins and targets aberrant species for destruction.
Keywords:Cell Nucleus, Genome, Mutation, Nuclear Proteins, Proteome, Saccharomyces Cerevisiae, Saccharomyces Cerevisiae Proteins, Signal Transduction, Ubiquitin-Protein Ligases
Source:Cell
ISSN:0092-8674
Publisher:Cell Press
Volume:120
Number:6
Page Range:734-736
Date:1 January 2005
Official Publication:https://doi.org/10.1016/j.cell.2005.03.003
PubMed:View item in PubMed

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