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Pardon me - No access without ubiquitin

PubMed:View item in PubMed
Creators Name:Sommer, T. and Jarosch, E.
Journal Title:Developmental Cell
Journal Abbreviation:Dev Cell
Volume:8
Number:1
Page Range:4-5
Date:1 January 2005
Keywords:Cell Nucleus Active Transport, Karyopherins, Signal Transduction, Ubiquitin, Ubiquitin-Conjugating Enzymes, Animals
Abstract:Spatial separation of ubiquitin conjugation pathways contributes to target-specific ubiquitination. Recently, Plafker et al. reported that importin 11-dependent nuclear import of the ubiquitin-conjugating enzyme UbcM2 occurs only if the latter is charged with ubiquitin. This interesting finding describes a link between nuclear transport pathways and ubiquitin and reveals a novel mechanism for localizing components of the ubiquitin system within the cell.
ISSN:1534-5807
Publisher:Cell Press (U.S.A.)
Item Type:Editorial

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