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Making tubes: Step by step

Item Type:Editorial
Title:Making tubes: Step by step
Creators Name:Rosario, M. and Birchmeier, W.
Abstract:Branched hollow tubes form the architectural basis of many mammalian organs. The growth factor HGF/SF and its receptor, the Met receptor tyrosine kinase, stimulate epithelial cells to undergo tubulogenesis in vitro. In this issue of Developmental Cell, O'Brien et al. (2004) look at temporal regulation and the role of two HGF/SF effectors, the ERK 1/2 MAP kinases and matrix metalloproteases, in this process.
Keywords:Epithelial Cells, Hepatocyte Growth Factor, Matrix Metalloproteinases, Mitogen-Activated Protein Kinases, Mitogens, Organogenesis, Proteins, Proto-Oncogene Proteins, Growth Factor Receptors, Viscera, Animals
Source:Developmental Cell
ISSN:1534-5807
Publisher:Cell Press (U.S.A.)
Volume:7
Number:1
Page Range:3-5
Date:1 July 2004
Official Publication:https://doi.org/10.1016/j.devcel.2004.06.015
PubMed:View item in PubMed

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