Die Rolle der Polychemotherapie im multimodalen Behandlungskonzept der malignen Knochentumoren [The role of polychemotherapy in the management of malignant bone tumors]

Item Type:	Article
Title:	Die Rolle der Polychemotherapie im multimodalen Behandlungskonzept der malignen Knochentumoren [The role of polychemotherapy in the management of malignant bone tumors]
Creators Name:	Reichardt, P. and Doerken, B.
Abstract:	Osteosarcoma,chondrosarcoma and Ewingtumors are the most common primary malignant bone tumors.Due to early hematogenous dissemination, surgery alone is able to cure less than 20% of patients with osteosarcoma. In Ewing-tumors less than 10% of patients will be cured with local treatment alone.By the use of aggressive polychemotherapy, given both pre- and post-surgery, cure rates of more than 50% for Ewing-tumors and about 70% for osteosarcoma could be achieved.Thus,chemotherapy is an indispensable part of the multimodal treatment of these tumor types. Chondrosarcomas are usually more highly differentiated and therefore show a lower rate of metastasis. The use of chemotherapy is not established in these tumors.
Keywords:	Osteosarcoma, Ewing Tumors, Chondrosarcoma, Multimodality Treatment, Polychemotherapy
Source:	Chirurg
ISSN:	0009-4722
Publisher:	Springer
Volume:	73
Number:	12
Page Range:	1170-1173
Date:	1 December 2002
Official Publication:	https://doi.org/10.1007/s00104-002-0555-9
PubMed:	View item in PubMed

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