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The InterPro Database, 2003 brings increased coverage and new features

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Item Type:Article
Title:The InterPro Database, 2003 brings increased coverage and new features
Creators Name:Mulder, N.J. and Apweiler, R. and Attwood, T.K. and Bairoch, A. and Barrell, D. and Bateman, A. and Binns, D. and Biswas, M. and Bradley, P. and Bork, P. and Bucher, P. and Copley, R.R. and Courcelle, E. and Das, U. and Durbin, R. and Falquet, L. and Fleischmann, W. and Griffiths-Jones, S. and Haft, D. and Harte, N. and Hulo, N. and Kahn, D. and Kanapin, A. and Krestyaninova, M. and Lopez, R. and Letunic, I. and Lonsdale, D. and Silventoinen, V. and Orchard, S.E. and Pagni, M. and Peyruc, D. and Ponting, C.P. and Selengut, J.D. and Servant, F. and Sigrist, C.J.A. and Vaughan, R. and Zdobnov, E.M.
Abstract:InterPro, an integrated documentation resource of protein families, domains and functional sites, was created in 1999 as a means of amalgamating the major protein signature databases into one comprehensive resource. PROSITE, Pfam, PRINTS, ProDom, SMART and TIGRFAMs have been manually integrated and curated and are available in InterPro for text- and sequence-based searching. The results are provided in a single format that rationalises the results that would be obtained by searching the member databases individually. The latest release of InterPro contains 5629 entries describing 4280 families, 1239 domains, 95 repeats and 15 post-translational modifications. Currently, the combined signatures in InterPro cover more than 74% of all proteins in SWISS-PROT and TrEMBL, an increase of nearly 15% since the inception of InterPro. New features of the database include improved searching capabilities and enhanced graphical user interfaces for visualisation of the data. The database is available via a webserver (http://www.ebi.ac.uk/interpro) and anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro).
Keywords:Computer Graphics, Protein Databases, Post-Translational Protein Processing, Tertiary Protein Structure, Proteins, Amino Acid Repetitive Sequences, User-Computer Interface, Animals
Source:Nucleic Acids Research
Publisher:Oxford University Press
Page Range:315-318
Date:1 January 2003
Official Publication:https://doi.org/10.1093/nar/gkg046
PubMed:View item in PubMed

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