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Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development

Official URL:https://doi.org/10.1016/S0952-7915(03)00014-1
PubMed:View item in PubMed
Creators Name:Mueller, G. and Lipp, M.
Journal Title:Current Opinion in Immunology
Journal Abbreviation:Curr Opin Immunol
Volume:15
Number:2
Page Range:217-224
Date:April 2003
Keywords:Chemokines, CC Chemokines, Lymph Nodes, Lymphocytes, Lymphoid Tissue, Lymphotoxin-Alpha, Immunological Models, Peyers Patches, Signal Transduction, Animals, Mice
Abstract:Chemokines are essential regulators of lymphocyte migration throughout the body. The chemokine system controls lymphocyte recirculation in immune-system homeostasis, as well as the activation-dependent and tissue-selective trafficking of effector and memory lymphocytes during immune responses. In addition, there is now substantial evidence that chemokines are critical factors for the development and organization of secondary lymphoid organs and that they are involved in all stages of lymphoid organogenesis.
ISSN:0952-7915
Publisher:Current Biology Ltd (England)
Item Type:Review

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