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Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development

Item Type:Review
Title:Concerted action of the chemokine and lymphotoxin system in secondary lymphoid-organ development
Creators Name:Mueller, G. and Lipp, M.
Abstract:Chemokines are essential regulators of lymphocyte migration throughout the body. The chemokine system controls lymphocyte recirculation in immune-system homeostasis, as well as the activation-dependent and tissue-selective trafficking of effector and memory lymphocytes during immune responses. In addition, there is now substantial evidence that chemokines are critical factors for the development and organization of secondary lymphoid organs and that they are involved in all stages of lymphoid organogenesis.
Keywords:Chemokines, CC Chemokines, Lymph Nodes, Lymphocytes, Lymphoid Tissue, Lymphotoxin-Alpha, Immunological Models, Peyers Patches, Signal Transduction, Animals, Mice
Source:Current Opinion in Immunology
ISSN:0952-7915
Publisher:Current Biology Ltd (England)
Volume:15
Number:2
Page Range:217-224
Date:April 2003
Official Publication:https://doi.org/10.1016/S0952-7915(03)00014-1
PubMed:View item in PubMed

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