Helmholtz Gemeinschaft


Sentinel lymphonodectomy in gastrointestinal cancer - where are we now?

Item Type:Review
Title:Sentinel lymphonodectomy in gastrointestinal cancer - where are we now?
Creators Name:Bembenek, A. and Bayraktar, S. and Gretschel, S. and Ulmer, C. and Schulze, T. and Markwardt, J. and Schneider, U. and Huenerbein, M. and Schlag, P.M.
Abstract:Up to now, no reliable methods for the pre- or intraoperative prediction of the nodal status are available in gastrointestinal cancer patients. Therefore, after the successful application of the sentinel lymph node concept in melanoma an breast cancer, ongoing research on this field is extended to gastrointestinal tumor entitiers. According to recent experiences, the most promising tumor entities are colon, gastric and anal cancer. First results with these patients indicate that the method could be reliable predictor of the nodal status and, thus, may have important future implications for the adjuvant therapy and the extent of surgery. The dye method for colon cancer and the combined method (dye and radiocolloid) for gastric cancer semm to be appropriate approaches, even when the general experience is still low. In rectal cancer, however, current experience failed yet to yield satisfying results. Up to now, anal cancer has not been a focus of publication, even when the concept seems to be very attractive for the evaluation of the inguinal lymph node status.
Keywords:Nodal Status, Lymph Node Status, Sentinel Lymph Node, Gastrointestinal Cancer, Colon Cancer, Rectal Cancer, Gastric Cancer, Anal Cancer
Publisher:Karger (Switzerland)
Page Range:334-340
Date:August 2002
Official Publication:https://doi.org/10.1159/000066050
PubMed:View item in PubMed

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