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A glucose-containing ether lipid (Glc-PAF) as an antiproliferative analogue of the platelet-activating factor

Item Type:Article
Title:A glucose-containing ether lipid (Glc-PAF) as an antiproliferative analogue of the platelet-activating factor
Creators Name:Mickeleit, M. and Wieder, T. and Arnold, M. and Geilen, C.C. and Mulzer, J. and Reutter, W.
Abstract:A new group of active substances, to which 1 belongs, inhibit cell proliferation and initiate programmed cell death (apoptosis) in keratinocytes. The glucosylated phospholipid 1 was synthesized from (S)-isopropylideneglycerol in nine steps with an overall yield of 25 %.
Keywords:Apoptosis, Glycosides, Phospholipids, Platelet-Activating Factor, Proliferation Inhibitors
Source:Angewandte Chemie International Edition
ISSN:1433-7851
Publisher:Wiley-VCH (Germany)
Volume:37
Number:3
Page Range:351-353
Date:16 February 1998
Official Publication:http://www3.interscience.wiley.com/journal/10004561/abstract

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