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A glucose-containing ether lipid (Glc-PAF) as an antiproliferative analogue of the platelet-activating factor

Item Type:Article
Title:A glucose-containing ether lipid (Glc-PAF) as an antiproliferative analogue of the platelet-activating factor
Creators Name:Mickeleit, M., Wieder, T., Arnold, M., Geilen, C.C., Mulzer, J. and Reutter, W.
Abstract:A new group of active substances, to which 1 belongs, inhibit cell proliferation and initiate programmed cell death (apoptosis) in keratinocytes. The glucosylated phospholipid 1 was synthesized from (S)-isopropylideneglycerol in nine steps with an overall yield of 25 %.
Keywords:Apoptosis, Glycosides, Phospholipids, Platelet-Activating Factor, Proliferation Inhibitors
Source:Angewandte Chemie International Edition
ISSN:1433-7851
Publisher:Wiley-VCH
Volume:37
Number:3
Page Range:351-353
Date:16 February 1998
Official Publication:https://doi.org/10.1002/(SICI)1521-3773(19980216)37:3<351::AID-ANIE351>3.0.CO;2-P
PubMed:View item in PubMed

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