CASH - a beta-helix domain widespread among carbohydrate-binding proteins

Item Type:	Article
Title:	CASH - a beta-helix domain widespread among carbohydrate-binding proteins
Creators Name:	Ciccarelli, F.D. and Copley, R.R. and Doerks, T. and Russell, R.B. and Bork, P.
Abstract:	In this article, we describe a novel, widespread domain (CASH) that is shared by many carbohydrate-binding proteins and sugar hydrolases. This domain occurs in more than 1000 proteins distributed among all three kingdoms of life. The CASH domain is characterized by internal repetitions of glycines and hydrophobic residues that correspond to the repetitive units of a predicted or observed right-handed β-helix structure of the pectate lyase superfamily.
Keywords:	Amino Acid Motifs, Binding Sites, Carbohydrate Metabolism, Carrier Proteins, Polysaccharide-Lyases, Protein Folding, Secondary Protein Structure, Tertiary Protein Structure, Animals
Source:	Trends in Biochemical Sciences
ISSN:	0968-0004
Publisher:	Elsevier
Volume:	27
Number:	2
Page Range:	59-62
Date:	1 January 2002
PubMed:	View item in PubMed

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