Alternative splicing and genome complexity

Item Type:	Article
Title:	Alternative splicing and genome complexity
Creators Name:	Brett, D. and Pospisil, H. and Valcarel, J. and Reich, J. and Bork, P.
Abstract:	Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.
Keywords:	Alternative Splicing, Expressed Sequence Tags, Genetic Variation, Genome, Messenger RNA, Animals, Cattle, Mice, Rats
Source:	Nature Genetics
ISSN:	1061-4036
Publisher:	Nature Publishing Group
Volume:	30
Number:	1
Page Range:	29-30
Date:	1 January 2002
Official Publication:	https://doi.org/10.1038/ng803
PubMed:	View item in PubMed

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