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Evolution of prokaryotic gene order: genome rearrangements in closely related species

Item Type:Article
Title:Evolution of prokaryotic gene order: genome rearrangements in closely related species
Creators Name:Suyama, M. and Bork, P.
Abstract:Conservation of gene order in prokaryotes has become important in predicting protein function because, over the evolutionary timescale, genomes are shuffled so that local gene-order conservation reflects the functional constraints within the protein. Here, we compare closely related genomes to identify the rate with which gene order is disrupted and to infer the genes involved in the genome rearrangement.
Keywords:Gene Rearrangement, Genome, Molecular Evolution, Prokaryotic Cells
Source:Trends in Genetics
ISSN:0168-9525
Publisher:Elsevier (The Netherlands)
Volume:17
Number:1
Page Range:10-13
Date:1 January 2001
PubMed:View item in PubMed

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