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The influence of cold stress on the myosin heavy chain expression of cardiac and smooth muscle in normotensive and spontaneously hypertensive female rats

Item Type:Article
Title:The influence of cold stress on the myosin heavy chain expression of cardiac and smooth muscle in normotensive and spontaneously hypertensive female rats
Creators Name:Adler, K. and Boels, P. and Ganten, U. and Ganten, D. and Morano, I.
Abstract:Cold exposure (6 weeks at 4 degrees C) of normotensive (Wistar-Kyoto) and stroke-prone spontaneously hypertensive female rats led to cardiac hypertrophy (in stroke-prone spontaneously hypertensive rats), increased the level of plasma thyroxine, and increased the alpha-myosin heavy chain expression in the left ventricle. In contrast, myosin heavy chain expression of both main mesenteric artery and uterus was not affected by cold stress and chronic hypertension, suggesting different regulation of myosin heavy chain expression in smooth and cardiac muscle in vivo.
Keywords:Western Blotting, Cardiomegaly, Cold, Isoenzymes, Smooth Muscle, Myocardium, Myosins, Stress, Triiodothyronine, Uterus, Animals, Rats
Source:Circulation Research
ISSN:0009-7330
Publisher:American Heart Association (U.S.A.)
Volume:69
Number:6
Page Range:1640-1644
Date:December 1991
Official Publication:http://circres.ahajournals.org/cgi/content/abstract/69/6/1640
PubMed:View item in PubMed

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