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| Item Type: | Article |
|---|---|
| Title: | SMART: a web-based tool for the study of genetically mobile domains |
| Creators Name: | Schultz, J. and Copley, R.R. and Doerks, T. and Ponting, C.P. and Bork, P. |
| Abstract: | SMART (a Simple Modular Architecture Research Tool) allows the identification and annotation of genetically mobile domains and the analysis of domain architectures (http://SMART.embl-heidelberg.de ). More than 400 domain families found in signalling, extra-cellular and chromatin-associated proteins are detectable. These domains are extensively annotated with respect to phyletic distributions, functional class, tertiary structures and functionally important residues. Each domain found in a non-redundant protein database as well as search parameters and taxonomic information are stored in a relational database system. User interfaces to this database allow searches for proteins containing specific combinations of domains in defined taxa. |
| Keywords: | Database Management Systems, Information Storage and Retrieval, Proteins, Chemistry, Sequence Alignment |
| Source: | Nucleic Acids Research |
| ISSN: | 0305-1048 |
| Publisher: | Oxford University Press |
| Volume: | 28 |
| Number: | 1 |
| Page Range: | 231-234 |
| Date: | 1 January 2000 |
| Official Publication: | http://nar.oxfordjournals.org/cgi/content/abstract/28/1/231 |
| PubMed: | View item in PubMed |
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