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A concise guide to choosing suitable gene expression systems for recombinant protein production

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Item Type:Review
Title:A concise guide to choosing suitable gene expression systems for recombinant protein production
Creators Name:Schütz, A., Bernhard, F., Berrow, N., Buyel, J.F., Ferreira-da-Silva, F., Haustraete, J., van den Heuvel, J., Hoffmann, J.E., de Marco, A., Peleg, Y., Suppmann, S., Unger, T., Vanhoucke, M., Witt, S. and Remans, K.
Abstract:This overview guides both novices and experienced researchers facing challenging targets to select the most appropriate gene expression system for producing a particular protein. By answering four key questions, readers can determine the most suitable gene expression system following a decision scheme. This guide addresses the most commonly used and accessible systems and provides brief descriptions of the main gene expression systems' key characteristics to assist decision making. Additionally, information has been included for selected less frequently used "exotic" gene expression systems.
Keywords:Pharmaceutical Databases, Gene Expression, Ligands, Recombinant Proteins
Source:STAR Protocols
ISSN:2666-1667
Publisher:Elsevier
Volume:4
Number:4
Page Range:102572
Date:15 December 2023
Official Publication:https://doi.org/10.1016/j.xpro.2023.102572
PubMed:View item in PubMed

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