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| Item Type: | Article |
|---|---|
| Title: | Mortality of neuromyelitis optica spectrum disorder patients in an Argentinean population: a study from the RelevarEM registry |
| Creators Name: | Carnero Contentti, E. and Lopez, P.A. and Pettinicchi, J.P. and Criniti, J. and Pappolla, A. and Miguez, J. and Cristiano, E. and Patrucco, L. and Liwacki, S. and Tkachuk, V. and Balbuena, M.E. and Vrech, C. and Deri, N. and Correale, J. and Marrodan, M. and Ysrraelit, M.C. and Leguizamon, F. and Luetic, G. and Menichini, M.L. and Tavolini, D. and Mainella, C. and Zanga, G. and Burgos, M. and Hryb, J. and Barboza, A. and Lazaro, L. and Alonso, R. and Fernández Liguori, N. and Nadur, D. and Alonso Serena, M. and Caride, A. and Paul, F. and Rojas, J.I. |
| Abstract: | We aimed to evaluate mortality and causes of death among Argentinean neuromyelitis optica spectrum disorder (NMOSD) patients and identify predictors of death. Retrospective study included 158 NMOSD patients and 11 (7%) patients died after 11 years of follow-up for a total exposure time of 53,345 days with an overall incidence density of 2.06 × 10.000 patients/day (95% CI 1.75-2.68). Extensive cervical myelitis with respiratory failure (45%) was the most frequent cause of death. Older age (HR = 2.05, p = 0.002) and higher disability score (HR = 2.30, p < 0.001) at disease onset were independent predictors of death. We found an 11-year mortality rate of 7% in Argentinean NMOSD patients. |
| Keywords: | Neuromyelitis Optica (NMO), Mortality, Latin America, Prognosis, Relapses |
| Source: | Multiple Sclerosis Journal Experimental Translational and Clinical |
| ISSN: | 2055-2173 |
| Publisher: | Sage Publications |
| Volume: | 9 |
| Number: | 4 |
| Page Range: | 20552173231205444 |
| Date: | 17 October 2023 |
| Official Publication: | https://doi.org/10.1177/20552173231205444 |
| PubMed: | View item in PubMed |
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