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Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charité fatigue center

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Item Type:Article
Title:Understanding, diagnosing, and treating Myalgic encephalomyelitis/chronic fatigue syndrome - State of the art: Report of the 2nd international meeting at the Charité fatigue center
Creators Name:Steiner, S. and Fehrer, A. and Hoheisel, F. and Schoening, S. and Aschenbrenner, A. and Babel, N. and Bellmann-Strobl, J. and Finke, C. and Fluge, Ø. and Froehlich, L. and Goebel, A. and Grande, B. and Haas, J.P. and Hohberger, B. and Jason, L.A. and Komaroff, A.L. and Lacerda, E. and Liebl, M. and Maier, A. and Mella, O. and Nacul, L. and Paul, F. and Prusty, B.K. and Puta, C. and Riemekasten, G. and Ries, W. and Rowe, P.C. and Sawitzki, B. and Shoenfeld, Y. and Schultze, J.L. and Seifert, M. and Sepúlveda, N. and Sotzny, F. and Stein, E. and Stingl, M. and Ufer, F. and Veauthier, C. and Westermeier, F. and Wirth, K. and Wolfarth, B. and Zalewski, P. and Behrends, U. and Scheibenbogen, C.
Abstract:Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a devastating disease affecting millions of people worldwide. Due to the 2019 pandemic of coronavirus disease (COVID-19), we are facing a significant increase of ME/CFS prevalence. On May 11th to 12th, 2023, the second international ME/CFS conference of the Charité Fatigue Center was held in Berlin, Germany, focusing on pathomechanisms, diagnosis, and treatment. During the two-day conference, more than 100 researchers from various research fields met on-site and over 700 attendees participated online to discuss the state of the art and novel findings in this field. Key topics from the conference included: the role of the immune system, dysfunction of endothelial and autonomic nervous system, and viral reactivation. Furthermore, there were presentations on innovative diagnostic measures and assessments for this complex disease, cutting-edge treatment approaches, and clinical studies. Despite the increased public attention due to the COVID-19 pandemic, the subsequent rise of Long COVID-19 cases, and the rise of funding opportunities to unravel the pathomechanisms underlying ME/CFS, this severe disease remains highly underresearched. Future adequately funded research efforts are needed to further explore the disease etiology and to identify diagnostic markers and targeted therapies.
Keywords:Chronic Fatigue Syndrome, Pandemics, Post-Acute COVID-19 Syndrome, Prevalence
Source:Autoimmunity Reviews
ISSN:1568-9972
Publisher:Elsevier
Volume:22
Number:11
Page Range:103452
Date:November 2023
Official Publication:https://doi.org/10.1016/j.autrev.2023.103452
PubMed:View item in PubMed

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