Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis

Item Type:	Editorial
Title:	Systematic perturbation of chromatin factors identifies regulatory networks during healthy and malignant hematopoiesis
Creators Name:	Solé-Boldo, L. and Haas, S.
Abstract:	In this issue of Nature Genetics, Lara-Astiaso et al. systematically characterized the functional roles of several chromatin factors in hematopoiesis by combining functional CRISPR screens with single-cell transcriptomics and chromatin accessibility profiling, revealing lineage biases and relationships with important transcription factors.
Keywords:	Epigenetics, Stem Cells
Source:	Nature Genetics
ISSN:	1061-4036
Publisher:	Nature Publishing Group
Volume:	55
Number:	9
Page Range:	1430-1431
Date:	September 2023
Official Publication:	https://doi.org/10.1038/s41588-023-01478-9
PubMed:	View item in PubMed

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