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Polymer models of the chromosomes in the nucleus of cells

Item Type:Book Section
Title:Polymer models of the chromosomes in the nucleus of cells
Creators Name:Chiariello, A.M. and Bianco, S. and Piccolo, A. and Annunziatella, C. and Barbieri, M. and Pombo, A. and Nicodemi, M.
Abstract:Berlin-BuchChromosomes have a complex organization in the space of the nucleus of cells. Understanding their structure is a key open issue in molecular biology. Quantitative models from polymer physics, investigated by extensive Monte Carlo and molecular dynamics simulations, have been developed to find the principles of chromosome folding and its function. Here, we provide a short review of recent progress in such an important research field.
Title of Book:High Performance Scientific Computing Using Distributed Infrastructures
Publisher:World Scientific Publishing Co.
Page Range:239-248
Number of Pages:528
Date:January 2017
Official Publication:https://doi.org/10.1142/9789814759717_0021

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