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| Item Type: | Article |
|---|---|
| Title: | Heterogeneity of diabetes: β-cells, phenotypes, and precision medicine: proceedings of an international symposium of the canadian institutes of Health Research’s Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases |
| Creators Name: | Cefalu, W.T. and Andersen, D.K. and Arreaza-Rubín, G. and Pin, C.L. and Sato, S. and Verchere, C.B. and Woo, M. and Rosenblum, N.D. and Rosenblum, N. and Cefalu, W. and Andersen, D.K. and Arreaza-Rubín, G. and Dhara, C. and James, S.P. and Makarchuk, M.J. and Pin, C.L. and Sato, S. and Verchere, B. and Woo, M. and Powers, A. and Estall, J. and Hoesli, C. and Millman, J. and Linnemann, A. and Johnson, J. and Pin, C.L. and Hawkins, M. and Woo, M. and Gloyn, A. and Cefalu, W. and Rosenblum, N. and Huising, M.O. and Benninger, R.K.P. and Almaça, J. and Hull-Meichle, R.L. and MacDonald, P. and Lynn, F. and Melero-Martin, J. and Yoshihara, E. and Stabler, C. and Sander, M. and Evans-Molina, C. and Engin, F. and Thompson, P. and Shalev, A. and Redondo, M.J. and Nadeau, K. and Bellin, M. and Udler, M.S. and Dennis, J. and Dash, S. and Zhou, W. and Snyder, M. and Booth, G. and Butte, A. and Florez, J. |
| Abstract: | One hundred years have passed since the discovery of insulin - an achievement that transformed diabetes from a fatal illness into a manageable chronic condition. The decades since that momentous achievement have brought ever more rapid innovation and advancement in diabetes research and clinical care. To celebrate the important work of the past century and help to chart a course for its continuation into the next, the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases recently held a joint international symposium, bringing together a cohort of researchers with diverse interests and backgrounds from both countries and beyond to discuss their collective quest to better understand the heterogeneity of diabetes and thus gain insights to inform new directions in diabetes treatment and prevention. This article summarizes the proceedings of that symposium, which spanned cutting-edge research into various aspects of islet biology, the heterogeneity of diabetic phenotypes, and the current state of and future prospects for precision medicine in diabetes. |
| Keywords: | Canada, Diabetes Mellitus, National Institute of Diabetes and Digestive and Kidney Diseases (U.S.), National Institutes of Health (U.S.), Phenotype, Precision Medicine, United States |
| Source: | Canadian Journal of Diabetes |
| ISSN: | 1499-2671 |
| Publisher: | Elsevier |
| Volume: | 45 |
| Number: | 8 |
| Page Range: | 697-713 |
| Date: | December 2021 |
| Official Publication: | https://doi.org/10.1016/j.jcjd.2021.09.126 |
| PubMed: | View item in PubMed |
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