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A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus

Item Type:Editorial
Title:A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus
Creators Name:Wang, G. and Sander, M.
Abstract:Pancreatic β-cell dysfunction contributes to type 2 diabetes mellitus (T2DM) pathogenesis. However, human islet studies have revealed few consistent molecular changes in T2DM, owing partly to technical and biological confounding factors. A new multi-omics study of islets from well-phenotyped living donors attempts to overcome these limitations to catalogue T2DM-associated molecular changes.
Keywords:Gene Expression Analysis, Type 2 Diabetes
Source:Nature Reviews Endocrinology
ISSN:1759-5029
Publisher:Springer Nature
Volume:17
Number:11
Page Range:641-642
Date:November 2021
Official Publication:https://doi.org/10.1038/s41574-021-00556-4
PubMed:View item in PubMed

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