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Epigenetics and epigenomics: implications for diabetes and obesity

Item Type:Article
Title:Epigenetics and epigenomics: implications for diabetes and obesity
Creators Name:Rosen, E.D. and Kaestner, K.H. and Natarajan, R. and Patti, M.E. and Sallari, R. and Sander, M. and Susztak, K.
Abstract:The American Diabetes Association convened a research symposium, "Epigenetics and Epigenomics: Implications for Diabetes and Obesity" on 17-19 November 2017. International experts in genetics, epigenetics, computational biology, and physiology discussed the current state of understanding of the relationships between genetics, epigenetics, and environment in diabetes and examined existing evidence for the role of epigenetic factors in regulating metabolism and the risk of diabetes and its complications. The authors summarize the presentations, which highlight how the complex interactions between genes and environment may in part be mediated through epigenetic changes and how information about nutritional and other environmental stimuli can be transmitted to the next generation. In addition, the authors present expert consensus on knowledge gaps and research recommendations for the field.
Keywords:DNA Methylation, Diabetes Mellitus, Genetic Epigenesis, Epigenomics, Obesity
Publisher:American Diabetes Association
Page Range:1923-1931
Date:1 October 2018
Additional Information:Copyright © 2018 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.
Official Publication:https://doi.org/10.2337/db18-0537
External Fulltext:View full text on PubMed Central
PubMed:View item in PubMed

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