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Cellular hierarchies predict drug response in acute myeloid leukemia

Item Type:Comment
Title:Cellular hierarchies predict drug response in acute myeloid leukemia
Creators Name:Raffel, S. and Velten, L. and Haas, S.
Abstract:In a recent Nature Medicine study, Zeng and colleagues integrate both genomic and stem cell models of acute myeloid leukemia (AML) by deconvoluting cellular hierarchies of more than 1,000 AML samples. This work introduces a framework capable of predicting drug responses to targeted therapies in future clinical trials.
Keywords:Acute Myeloid Leukemia, Neoplastic Stem Cells
Source:Cancer Cell
ISSN:1535-6108
Publisher:Cell Press / Elsevier
Volume:40
Number:9
Page Range:917-919
Date:12 September 2022
Official Publication:https://doi.org/10.1016/j.ccell.2022.08.019
PubMed:View item in PubMed

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