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Transient activated fibroblasts contribute to zebrafish heart regeneration

Item Type:Editorial
Title:Transient activated fibroblasts contribute to zebrafish heart regeneration
Creators Name:Junker, J.P. and Panáková, D.
Abstract:In the zebrafish heart, several transient fibroblast types appear after injury. High-throughput lineage tracing revealed that injury-responsive fibroblasts are derived from two distinct lineage origins: the epicardium and the endocardium. Targeted cell-type-specific depletion showed that at least one fibroblast type has a critical role in heart regeneration.
Keywords:Animals, Zebrafish
Source:Nature Genetics
ISSN:1061-4036
Publisher:Nature Publishing Group
Volume:54
Number:8
Page Range:1076-1077
Date:August 2022
Official Publication:https://doi.org/10.1038/s41588-022-01130-y
PubMed:View item in PubMed

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