Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

The blood-brain barrier-a metabolic ecosystem

Item Type:Editorial
Title:The blood-brain barrier-a metabolic ecosystem
Creators Name:Castro, M. and Potente, M.
Abstract:A functional blood-brain barrier relies on a tightly controlled interplay between endothelial cells, pericytes, and astrocytes, which together form the neurovascular unit. Recent work by Lee et al (2022) discovers endothelial cell-derived lactate as a crucial metabolic fuel for brain pericytes, revealing a new way of CNS vascular communication that links nutrient metabolism to blood-brain barrier function.
Keywords:Astrocytes, Blood-Brain Barrier, Brain, Ecosystem, Endothelial Cells, Pericytes / Metabolism
Source:EMBO Journal
ISSN:0261-4189
Publisher:EMBO Press
Volume:41
Number:9
Page Range:e111189
Date:2 May 2022
Official Publication:https://doi.org/10.15252/embj.2022111189
PubMed:View item in PubMed

Repository Staff Only: item control page

Open Access
MDC Library