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Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening

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Item Type:Letter
Title:Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyocytes and preclinical drug screening
Creators Name:El-Battrawy, I. and Lan, H. and Cyganek, L. and Maywald, L. and Zhong, R. and Zhang, F. and Xu, Q. and Lee, J. and Duperrex, E. and Hierlemann, A. and Saguner, A.M. and Duru, F. and Kovacs, B. and Huang, M. and Liao, Z. and Albers, S. and Müller, J. and Dinkel, H. and Rose, L. and Hohn, A. and Yang, Z. and Qiao, L. and Li, Y. and Lang, S. and Kleinsorge, M. and Mügge, A. and Aweimer, A. and Fan, X. and Diecke, S. and Akin, I. and Li, G. and Zhou, X.
Keywords:Brugada Syndrome, Cardiac Death, Channelopathy, Short QT Syndrome
Source:Clinical and Translational Medicine
ISSN:2001-1326
Publisher:Wiley
Volume:11
Number:12
Page Range:e646
Date:26 December 2021
Official Publication:https://doi.org/10.1002/ctm2.646
PubMed:View item in PubMed

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