Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

Targeted resequencing reveals genomic signatures of barley domestication

[thumbnail of Original Article]
Preview
PDF (Original Article) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
7MB
[thumbnail of Supporting Information] Other (Supporting Information)
20MB

Item Type:Article
Title:Targeted resequencing reveals genomic signatures of barley domestication
Creators Name:Pankin, A., Altmüller, J., Becker, C. and von Korff, M.
Abstract:Barley (Hordeum vulgare) is an established model to study domestication of the Fertile Crescent cereals. Recent molecular data suggested that domesticated barley genomes consist of the ancestral blocks descending from multiple wild barley populations. However, the relationship between the mosaic ancestry patterns and the process of domestication itself remained unclear. To address this knowledge gap, we identified candidate domestication genes using selection scans based on targeted resequencing of 433 wild and domesticated barley accessions. We conducted phylogenetic, population structure, and ancestry analyses to investigate the origin of the domesticated barley haplotypes separately at the neutral and candidate domestication loci. We discovered multiple selective sweeps that occurred on all barley chromosomes during domestication in the background of several ancestral wild populations. The ancestry analyses demonstrated that, although the ancestral blocks of the domesticated barley genomes were descended from all over the Fertile Crescent, the candidate domestication loci originated specifically in its eastern and western parts. These findings provided the first molecular evidence implicating multiple wild or protodomesticated lineages in the process of barley domestication initiated in the Levantine and Zagros clusters of the origin of agriculture.
Keywords:Ancestry Analysis, Barley, Cereals, Domestication, Selection Scan, Targeted Resequencing
Source:New Phytologist
ISSN:1469-8137
Publisher:Wiley
Volume:218
Number:3
Page Range:1247-1259
Date:May 2018
Official Publication:https://doi.org/10.1111/nph.15077
PubMed:View item in PubMed

Repository Staff Only: item control page

Downloads

Downloads per month over past year

Open Access
MDC Library