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Clinical and neuroimaging findings in MOGAD - MRI and OCT

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Item Type:Review
Title:Clinical and neuroimaging findings in MOGAD - MRI and OCT
Creators Name:Bartels, F. and Lu, A. and Oertel, F.C. and Finke, C. and Paul, F. and Chien, C.
Abstract:Myelin oligodendrocyte glycoprotein antibody associated disorders (MOGAD) are rare in both children and adults, and have been recently suggested to be an autoimmune neuroinflammatory group of disorders that are different from aquaporin-4 autoantibody associated neuromyelitis optica spectrum disorder and from classic multiple sclerosis. In vivo imaging of the MOGAD patient central nervous system has shown some distinguishing features when evaluating magnetic resonance imaging of the brain, spinal cord, optic nerves, as well as retinal imaging using optical coherence tomography. In this review, we discuss key clinical and neuroimaging characteristics of paediatric and adult MOGAD. We describe how these imaging techniques may be used to study this group of disorders and discuss how image analysis methods have led to recent insights for consideration in future studies.
Keywords:Myelin Oligodendrocyte Glycoprotein Associated Disorders, Magnetic Resonance Imaging, Optical Coherence Tomography
Source:Clinical and Experimental Immunology
Page Range:266-281
Date:December 2021
Official Publication:https://doi.org/10.1111/cei.13641
PubMed:View item in PubMed

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