A resource of targeted mutant mouse lines for 5,061 genes

Birling, M.C.; Yoshiki, A.; Adams, D.J.; Ayabe, S.; Beaudet, A.L.; Bottomley, J.; Bradley, A.; Brown, S.D.M.; Bürger, A.; Bushell, W.; Chiani, F.; Chin, H.J.G.; Christou, S.; Codner, G.F.; DeMayo, F.J.; Dickinson, M.E.; Doe, B.; Donahue, L.R.; Fray, M.D.; Gambadoro, A.; Gao, X.; Gertsenstein, M.; Gomez-Segura, A.; Goodwin, L.O.; Heaney, J.D.; Hérault, Y.; de Angelis, M.H.; Jiang, S.T.; Justice, M.J.; Kasparek, P.; King, R.E.; Kühn, R.; Lee, H.; Lee, Y.J.; Liu, Z.; Lloyd, K.C.K.; Lorenzo, I.; Mallon, A.M.; McKerlie, C.; Meehan, T.F.; Fuentes, V.M.; Newman, S.; Nutter, L.M.J.; Oh, G.T.; Pavlovic, G.; Ramirez-Solis, R.; Rosen, B.; Ryder, E.J.; Santos, L.A.; Schick, J.; Seavitt, J.R.; Sedlacek, R.; Seisenberger, C.; Seong, J.K.; Skarnes, W.C.; Sorg, T.; Steel, K.P.; Tamura, M.; Tocchini-Valentini, G.P.; Wang, C.K.L.; Wardle-Jones, H.; Wattenhofer-Donzé, M.; Wells, S.; Wiles, M.V.; Willis, B.J.; Wood, J.A.; Wurst, W.; Xu, Y.; Teboul, L.; Murray, S.A.

A resource of targeted mutant mouse lines for 5,061 genes

Tools

Item Type:	Editorial
Title:	A resource of targeted mutant mouse lines for 5,061 genes
Creators:	Birling, M.C., Yoshiki, A. ORCID: https://orcid.org/0000-0002-9450-5151, Adams, D.J. ORCID: https://orcid.org/0000-0001-9490-0306, Ayabe, S. ORCID: https://orcid.org/0000-0003-2737-5315, Beaudet, A.L., Bottomley, J., Bradley, A., Brown, S.D.M., Bürger, A., Bushell, W., Chiani, F. ORCID: https://orcid.org/0000-0002-8887-3900, Chin, H.J.G., Christou, S., Codner, G.F., DeMayo, F.J., Dickinson, M.E., Doe, B., Donahue, L.R., Fray, M.D., Gambadoro, A., Gao, X., Gertsenstein, M., Gomez-Segura, A., Goodwin, L.O., Heaney, J.D., Hérault, Y. ORCID: https://orcid.org/0000-0001-7049-6900, de Angelis, M.H. ORCID: https://orcid.org/0000-0002-7898-2353, Jiang, S.T., Justice, M.J. ORCID: https://orcid.org/0000-0003-3562-2099, Kasparek, P., King, R.E. ORCID: https://orcid.org/0000-0001-6733-8805, Kühn, R. ORCID: https://orcid.org/0000-0003-1694-9803, Lee, H., Lee, Y.J. ORCID: https://orcid.org/0000-0002-3841-1994, Liu, Z., Lloyd, K.C.K. ORCID: https://orcid.org/0000-0002-5318-4144, Lorenzo, I., Mallon, A.M., McKerlie, C. ORCID: https://orcid.org/0000-0002-2232-0967, Meehan, T.F., Fuentes, V.M. ORCID: https://orcid.org/0000-0003-3574-546X, Newman, S., Nutter, L.M.J. ORCID: https://orcid.org/0000-0001-9619-146X, Oh, G.T. ORCID: https://orcid.org/0000-0002-1104-1698, Pavlovic, G. ORCID: https://orcid.org/0000-0001-9122-4592, Ramirez-Solis, R., Rosen, B., Ryder, E.J., Santos, L.A., Schick, J. ORCID: https://orcid.org/0000-0002-8623-4910, Seavitt, J.R., Sedlacek, R. ORCID: https://orcid.org/0000-0002-3352-392X, Seisenberger, C., Seong, J.K., Skarnes, W.C., Sorg, T., Steel, K.P., Tamura, M., Tocchini-Valentini, G.P., Wang, C.K.L., Wardle-Jones, H., Wattenhofer-Donzé, M. ORCID: https://orcid.org/0000-0002-6092-274X, Wells, S., Wiles, M.V., Willis, B.J., Wood, J.A., Wurst, W., Xu, Y. ORCID: https://orcid.org/0000-0002-6689-7768, Teboul, L. ORCID: https://orcid.org/0000-0002-2789-8637 and Murray, S.A. ORCID: https://orcid.org/0000-0002-0594-1702
Abstract:	The International Mouse Phenotyping Consortium reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter alleles.
Keywords:	Gene Deletion, Genetic Association Studies, Genome, Genotype, Information Dissemination, International Cooperation, Internet, Knockout Mice, Mouse Embryonic Stem Cells, Mutagenesis, Phenotype, Animals, Mice
Source:	Nature Genetics
ISSN:	1061-4036
Publisher:	Nature Publishing Group
Volume:	53
Number:	4
Page Range:	416-419
Date:	April 2021
Official Publication:	https://doi.org/10.1038/s41588-021-00825-y
PubMed:	View item in PubMed

Repository Staff Only: item control page