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ASHLEYS: automated quality control for single-cell Strand-seq data

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Item Type:Article
Title:ASHLEYS: automated quality control for single-cell Strand-seq data
Creators Name:Eimer, C. and Sanders, A.D. and Korbel, J.O. and Marschall, T. and Ebert, P.
Abstract:Single-cell DNA template strand sequencing (Strand-seq) enables chromosome length haplotype phasing, construction of phased assemblies, mapping sister-chromatid exchange events and structural variant discovery. The initial quality control of potentially thousands of single-cell libraries is still done manually by domain experts. ASHLEYS automates this tedious task, delivers near-expert performance and labels even large data sets in seconds. AVAILABILITY AND IMPLEMENTATION: github.com/friendsofstrandseq/ashleys-qc, MIT license.
Source:Bioinformatics
ISSN:1367-4803
Publisher:Oxford University Press
Page Range:btab221
Date:1 April 2021
Official Publication:https://doi.org/10.1093/bioinformatics/btab221
PubMed:View item in PubMed

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