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Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective]

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Item Type:Review
Title:Humane neuromuskuläre Organoide - Anwendung und Perspektive [Human neuromuscular organoids - Application and perspective]
Creators Name:Faustino Martins, J.M., Nguyen, L.V.N. and Gouti, M.
Abstract:Organoids are miniature, organ-like structures derived from stem cells. While techniques for developing organoids for different tissues have advanced in the past decade, it has remained a challenge to simultaneously grow two different tissues into a single functional organoid. We have recently developed a 3D neuromuscular organoid that allows the simultaneous generation of spinal neurons and skeletal muscles. Here we discuss their future applications in modeling neuromuscular disorders.
Source:BIOspektrum
ISSN:0947-0867
Publisher:Springer / Spektrum Akademischer Verlag
Volume:27
Number:2
Page Range:135-138
Date:March 2021
Official Publication:https://doi.org/10.1007/s12268-021-1553-0

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