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Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications

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Item Type:Review
Title:Endovascular treatment of carotid artery stenosis: evidences from randomized controlled trials and actual indications
Creators Name:Ilardi, F. and Magliulo, F. and Gargiulo, G. and Schiattarella, G.G. and Carotenuto, G. and Serino, F. and Ferrone, M. and Visco, E. and Scudiero, F. and Carbone, A. and Perrino, C. and Trimarco, B. and Esposito, G.
Abstract:Atherosclerotic stenosis of common and internal carotid arteries is a well-recognized risk factor for ischemic stroke, and revascularization has been proven to be the main tool of prevention, particularly for patients with stenosis-related symptoms. While for many years surgical carotid endarterectomy (CEA) has been considered the gold-standard strategy to restore vascular patency, recently the endovascular treatment through percutaneous angioplasty and stent implantation (CAS) has become a valid alternative. In the last years, interesting data about the comparison of these strategies have emerged. CAS seems to cause more peri-procedural strokes, but may also avoid many adverse events related to surgery and general anaesthesia, including peri-procedural myocardial infarction. For these reasons, it was initially considered a second-choice strategy to be adopted in patients for whom surgery was contraindicated. However, more recent trials have shown that CAS might be considered an effective alternative to CEA. Moreover, the rapid evolution of CAS technique and materials suggests its potential to improve outcome and possible superiority compared to CEA in the next future. Purpose of this review is to discuss the most recent clinical evidences concerning the treatment of carotid artery stenosis, with a special focus on the endovascular treatment.
Keywords:Carotid, Stenosis, Endovascular, CEA, CAS, CREST
Source:Monaldi Archives for Chest Disease
Publisher:Fondazione Salvatore Maugeri
Page Range:183-191
Date:December 2011
Official Publication:https://doi.org/10.4081/monaldi.2011.175
PubMed:View item in PubMed

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