Renal blood flow using arterial spin labeling (ASL) MRI: experimental protocol and principles

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Item Type:

Article

Title:

Renal blood flow using arterial spin labeling (ASL) MRI: experimental protocol and principles

Creators Name:

Chuang, K.H. and Meier, M. and Fernández-Seara, M.A. and Kober, F. and Ku, M.C.

Abstract:

A noninvasive, robust, and reproducible method to measure renal perfusion is important to understand the physiology of kidney. Arterial spin labeling (ASL) MRI technique labels the endogenous blood water as freely diffusible tracers to measure perfusion quantitatively without relying on exogenous contrast agent. Therefore, it alleviates the safety concern involving gadolinium chelates. To obtain quantitative tissue perfusion information is particularly relevant for multisite and longitudinal imaging of living subjects.This chapter is based upon work from the PARENCHIMA COST Action, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This experimental protocol chapter is complemented by two separate chapters describing the basic concept and data analysis.

Keywords:

Magnetic Resonance Imaging (MRI), Kidney, Arterial Spin Labeling (ASL), Animals, Mice

Source:

Methods in Molecular Biology

Series Name:

Methods in Molecular Biology

Title of Book:

Preclinical MRI of the kidney : methods and protocols

ISSN:

1064-3745

ISBN:

978-1-0716-0977-4

Publisher:

Springer / Humana Press

Volume:

2216

Page Range:

443-453

Date:

2021

Official Publication:

https://doi.org/10.1007/978-1-0716-0978-1_26

PubMed:

View item in PubMed

Related to:

URL	URL Type
https://edoc.mdc-berlin.de/19922/	Book

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