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An intrinsic interferon program protects stem cells from viral infection

Item Type:Editorial
Title:An intrinsic interferon program protects stem cells from viral infection
Creators Name:Haas, S. and Trumpp, A.
Abstract:Specific protection mechanisms are required to safeguard stem cell integrity. In a recent issue of Cell, Wu et al. (2018) show that stem cells are equipped with high intrinsic expression of interferon-stimulated genes (ISGs) but remain refractory to acute interferon signaling. This protects stem cells from viral infection.
Keywords:Interferons, Stem Cells
Source:Developmental Cell
ISSN:1534-5807
Publisher:Cell Press
Volume:44
Number:3
Page Range:279-280
Date:5 February 2018
Official Publication:https://doi.org/10.1016/j.devcel.2018.01.013
PubMed:View item in PubMed

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