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The role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a Position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC)

Item Type:Article
Title:The role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a Position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC)
Creators Name:Čelutkienė, J. and Pudil, R. and López-Fernández, T. and Grapsa, J. and Nihoyannopoulos, P. and Bergler-Klein, J. and Cohen-Solal, A. and Farmakis, D. and Tocchetti, C.G. and von Haehling, S. and Barberis, V. and Flachskampf, F.A. and Čeponienė, I. and Haegler-Laube, E. and Suter, T. and Lapinskas, T. and Prasad, S. and de Boer, R.A. and Wechalekar, K. and Anker, M.S. and Iakobishvili, Z. and Buccarelli-Ducci, C. and Schulz-Menger, J. and Cosyns, B. and Gaemperli, O. and Belenkov, Y. and Hulot, J.S. and Galderisi, M. and Lancellotti, P. and Bax, J. and Marwick, T.H. and Chioncel, O. and Jaarsma, T. and Mullens, W. and Piepoli, M. and Thum, T. and Heymans, S. and Mueller, C. and Moura, B. and Ruschitzka, F. and Zamorano, J.L. and Rosano, G. and Coats, A.J.S. and Asteggiano, R. and Seferovic, P. and Edvardsen, T. and Lyon, A.R.
Abstract:Cardiovascular (CV) imaging is an important tool in baseline risk assessment and detection of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position statement examines the role of echocardiography, cardiac magnetic resonance, nuclear cardiac imaging and computed tomography in the management of cancer patients. The Imaging and Cardio-Oncology Study Groups of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) in collaboration with the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the ESC have evaluated the current evidence for the value of modern CV imaging in the cardio-oncology field. The most relevant echocardiographic parameters, including global longitudinal strain and three-dimensional ejection fraction, are proposed. The protocol for baseline pre-treatment evaluation and specific surveillance algorithms or pathways for anthracycline chemotherapy, HER2-targeted therapies such as trastuzumab, vascular endothelial growth factor tyrosine kinase inhibitors, BCr-Abl tyrosine kinase inhibitors, proteasome inhibitors and immune checkpoint inhibitors are presented. The indications for CV imaging after completion of oncology treatment are considered. The typical consequences of radiation therapy and the possibility of their identification in the long-term are also summarized. Special populations are discussed including female survivors planning pregnancy, patients with carcinoid disease, patients with cardiac tumours and patients with right heart failure. Future directions and ongoing CV imaging research in cardio-oncology are discussed. This article is protected by copyright. All rights reserved.
Keywords:Imaging, Cardio-Oncology, Cardiotoxicity, Heart Failure, Echocardiography, Cardiac Magnetic Resonance, Computed Tomography, Global Longitudinal Strain, Nuclear Imaging
Source:European Journal of Heart Failure
ISSN:1388-9842
Publisher:Wiley
Volume:22
Number:9
Page Range:1504-1524
Date:September 2020
Official Publication:https://doi.org/10.1002/ejhf.1957
PubMed:View item in PubMed

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