Selbst berichtete Infektionen in der NAKO Gesundheitsstudie - Einordnung in die gegenwärtige Forschungslandschaft [Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape]

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Item Type:	Article
Title:	Selbst berichtete Infektionen in der NAKO Gesundheitsstudie - Einordnung in die gegenwärtige Forschungslandschaft [Self-reported infections in the German National Cohort (GNC) in the context of the current research landscape]
Creators Name:	Hassenstein, M.J. and Aarabi, G. and Ahnert, P. and Becher, H. and Franzke, C.-W. and Fricke, J. and Krause, G. and Glöckner, S. and Gottschick, C. and Karch, A. and Kemmling, Y. and Kerrinnes, T. and Lange, B. and Mikolajczyk, R. and Nieters, A. and Ott, J.J. and Ahrens, W. and Berger, K. and Meinke-Franze, C. and Gastell, S. and Günther, K. and Greiser, K.H. and Holleczek, B. and Horn, J. and Jaeschke, L. and Jagodzinski, A. and Jansen, L. and Jochem, C. and Jöckel, K.H. and Kaaks, R. and Krist, L. and Kuß, O. and Langer, S. and Legath, N. and Leitzmann, M. and Lieb, W. and Loeffler, M. and Mangold, N. and Michels, K.B. and Meisinger, C. and Obi, N. and Pischon, T. and Schikowski, T. and Schipf, S. and Schulze, M.B. and Stang, A. and Waniek, S. and Wirkner, K. and Willich, S.N. and Castell, S.
Abstract:	BACKGROUND: Infectious diseases continue to play an important role for disease perception, health-economic considerations and public health in Germany. In recent years, infectious diseases have been linked to the development of non-communicable diseases. Analyses of the German National Cohort (GNC) may provide deeper insights into this issue and pave the way for new targeted approaches in disease prevention. OBJECTIVES: The aim was to describe the tools used to assess infectious diseases and to present initial data on infectious disease frequencies, as well as to relate the GNC assessment tools to data collection methods in other studies in Germany. METHODS: As part of the baseline examination, questions regarding infectious diseases were administered using both an interview and a self-administered touchscreen questionnaire. Data from the initial 101,787 GNC participants were analysed. RESULTS: In the interview, 0.2% (HIV/AIDS) to 8.6% (shingles) of respondents reported ever having a medical diagnosis of shingles, postherpetic neuralgia (in cases where shingles was reported), hepatitis B/C, HIV/AIDS, tuberculosis or sepsis if treated in hospital. In the questionnaire, 12% (cystitis) to 81% (upper respiratory tract infections) of respondents reported having experienced at least one occurrence of upper or lower respiratory tract infections, gastrointestinal infections, cystitis or fever within the past 12 months. OUTLOOK: The cross-sectional analyses of data and tools presented here - for example on determinants of susceptibility to self-reported infections - can be anticipated from the year 2021 onward. Beyond that, more extensive research into infectious disease epidemiology will follow, particularly once analyses of GNC biological materials have been performed.
Keywords:	Infectious Diseases, Infectious Disease Epidemiology, German National Cohort (GNC), Cohort Study, Communicable Diseases, Epidemiology
Source:	Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
ISSN:	1436-9990
Publisher:	Springer
Volume:	63
Number:	4
Page Range:	404-414
Date:	April 2020
Official Publication:	https://doi.org/10.1007/s00103-020-03114-x
PubMed:	View item in PubMed

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