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Fast myocardial T(1) mapping using cardiac motion correction

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Item Type:Article
Title:Fast myocardial T(1) mapping using cardiac motion correction
Creators Name:Becker, K.M. and Blaszczyk, E. and Funk, S. and Nuesslein, A. and Schulz-Menger, J. and Schaeffter, T. and Kolbitsch, C.
Abstract:PURPOSE: To improve the efficiency of native and postcontrast high-resolution cardiac T(1) mapping by utilizing cardiac motion correction. METHODS: Common cardiac T(1) mapping techniques only acquire data in a small part of the cardiac cycle, leading to inefficient data sampling. Here, we present an approach in which 80% of each cardiac cycle is used for T(1) mapping by integration of cardiac motion correction. Golden angle radial data was acquired continuously for 8 s with in-plane resolution of 1.3 × 1.3 mm(2). Cine images were reconstructed for nonrigid cardiac motion estimation. Images at different TIs were reconstructed from the same data, and motion correction was performed prior to T(1) mapping. Native T(1) mapping was evaluated in healthy subjects. Furthermore, the technique was applied for postcontrast T(1) mapping in 5 patients with suspected fibrosis. RESULTS: Cine images with high contrast were obtained, leading to robust cardiac motion estimation. Motion-corrected T(1) maps showed myocardial T(1) times similar to cardiac-triggered T(1) maps obtained from the same data (1288 ± 49 ms and 1259 ± 55 ms, respectively) but with a 34% improved precision (spatial variation: 57.0 ± 12.5 ms and 94.8 ± 15.4 ms, respectively, P < 0.0001) due to the increased amount of data. In postcontrast T(1) maps, focal fibrosis could be confirmed with late contrast-enhancement images. CONCLUSION: The proposed approach provides high-resolution T(1) maps within 8 s. Data acquisition efficiency for T(1) mapping was improved by a factor of 5 by integration of cardiac motion correction, resulting in precise T(1) maps.
Keywords:Cine Imaging, Cardiovascular MR, Motion Correction, Myocardial Tissue Characterization, T(1) Mapping
Source:Magnetic Resonance in Medicine
Page Range:438-451
Date:February 2020
Official Publication:https://doi.org/10.1002/mrm.27935
PubMed:View item in PubMed

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