Helmholtz Gemeinschaft

Search
Browse
Statistics
Feeds

Interplay of Na(+) balance and immunobiology of dendritic cells

[img]
Preview
PDF (Original Article) - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
1MB

Item Type:Review
Title:Interplay of Na(+) balance and immunobiology of dendritic cells
Creators Name:Neubert, P. and Schröder, A. and Müller, D.N. and Jantsch, J.
Abstract:Local Na(+) balance emerges as an important factor of tissue microenvironment. On the one hand, immune cells impact on local Na(+) levels. On the other hand, Na(+) availability is able to influence immune responses. In contrast to macrophages, our knowledge of dendritic cells (DCs) in this state of affair is rather limited. Current evidence suggests that the impact of increased Na(+) on DCs is context dependent. Moreover, it is conceivable that DC immunobiology might also be influenced by Na(+)-rich-diet-induced changes of the gut microbiome.
Keywords:Dendritic Cells, Na(+) Balance, Antigen-Presentation, Nfat5, Kidney, Skin Microenvironment
Source:Frontiers in Immunology
ISSN:1664-3224
Publisher:Frontiers Media SA (Switzerland)
Volume:10
Page Range:599
Date:March 2019
Official Publication:https://doi.org/10.3389/fimmu.2019.00599
PubMed:View item in PubMed

Repository Staff Only: item control page

Downloads

Downloads per month over past year

Open Access
MDC Library