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In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI

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Item Type:Article
Title:In vivo myocardial tissue characterization of all four chambers using high-resolution quantitative MRI
Creators Name:Becker, K.M. and Schulz-Menger, J. and Schaeffter, T. and Kolbitsch, C.
Abstract:Quantitative native T(1) Mapping of the myocardium without the application of contrast agents can be used to detect fibrosis in the left ventricle. Spatial resolution of standard native T(1) mapping is limited by cardiac motion and hence is not sufficient to resolve small myocardial structures, such as the right ventricle and the atria. Here, we present a novel MR approach which provides cardiac motion information and native T(1) maps from the same data. Motion information is utilized to optimize data selection for T(1) mapping and a model-based iterative reconstruction scheme ensures high-resolution T(1) maps for the entire heart. Feasibility of the approach was demonstrated in three healthy volunteers. In the T(1) maps, the myocardium of all four chambers can be visualized and T(1) values of the left atrium and right chambers were comparable to left ventricular T(1) values.
Keywords:T(1) Mapping, Myocardial Tissue Characterization, Magnetic Resonance Imaging
Source:Current Directions in Biomedical Engineering
ISSN:2364-5504
Publisher:De Gruyter (Germany)
Volume:4
Number:1
Page Range:263-266
Date:1 September 2018
Official Publication:https://doi.org/10.1515/cdbme-2018-0064

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