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Item Type: | Article | ||||
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Title: | VGLUT2 functions as a differential marker for hippocampal output neurons | ||||
Creators Name: | Wozny, C. and Beed, P. and Nitzan, N. and Pössnecker, Y. and Rost, B.R. and Schmitz, D. | ||||
Abstract: | The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis. | ||||
Keywords: | Channelrhodopsin-2, Entorhinal Cortex, Hippocampus, Subiculum, Synaptic Transmission, VGLUT2, Animals, Mice | ||||
Source: | Frontiers in Cellular Neuroscience | ||||
ISSN: | 1662-5102 | ||||
Publisher: | Frontiers Media SA | ||||
Volume: | 12 | ||||
Page Range: | 337 | ||||
Date: | 2 October 2018 | ||||
Official Publication: | https://doi.org/10.3389/fncel.2018.00337 | ||||
PubMed: | View item in PubMed | ||||
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