VGLUT2 functions as a differential marker for hippocampal output neurons
| Item Type: | Preprint |
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| Title: | VGLUT2 functions as a differential marker for hippocampal output neurons |
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| Creators Name: | Wozny, C. and Beed, P. and Nitzan, N. and Poessnecker, Y. and Rost, B.R. and Schmitz, D. |
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| Abstract: | The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis. |
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| Keywords: | Channelrhodopsin-2, Entorhinal Cortex, Hippocampus, Subiculum, Synaptic Transmission, VGLUT2 |
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| Source: | bioRxiv |
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| Publisher: | Cold Spring Harbor Laboratory Press |
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| Article Number: | 348227 |
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| Date: | 17 June 2018 |
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| Official Publication: | https://doi.org/10.1101/348227 |
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| Related to: | |
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