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UnSASPing senescence: unmasking tumor suppression?

Item Type:Editorial
Title:UnSASPing senescence: unmasking tumor suppression?
Creators Name:Schmitt, C.A.
Abstract:Cellular senescence serves as a barrier to tumor development and a principle effector of anti-cancer therapy, but the largely pro-inflammatory senescence-associated secretory phenotype (SASP) may drive tumor promotion and contribute to age-related pathologies. In this issue of Cancer Cell, Georgilis et al. present SASP-deprived senescence as a potential therapeutic perspective.
Source:Cancer Cell
ISSN:1535-6108
Publisher:Cell Press (U.S.A.)
Volume:34
Number:1
Page Range:6-8
Date:9 July 2018
Official Publication:https://doi.org/10.1016/j.ccell.2018.06.009
PubMed:View item in PubMed

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