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A novel exploratory method for visual recombination detection

Item Type:Article
Title:A novel exploratory method for visual recombination detection
Creators Name:Strimmer, K. and Forslund, K. and Holland, B. and Moulton, V.
Abstract:A versatile visual approach for detecting recombination and identifying recombination breakpoints within a sequence alignment is presented. The method is based on two novel diagrams - the highway plot and the occupancy plot - that graphically portray phylogenetic inhomogeneity along an alignment, and can be viewed as a synthesis of two widely used but unrelated methods: bootscanning and quartet-mapping. To illustrate the method, simulated data and HIV-1 and influenza A datasets are investigated.
Keywords:Computational Biology, Computer Simulation, Genetic Databases, Genetic Models, Genetic Recombination, HIV-1, Orthomyxoviridae, Phylogeny, Sequence Alignment
Source:Genome Biology
ISSN:1474-760X
Publisher:BioMed Central (U.K.)
Volume:4
Number:5
Page Range:R33
Date:2003
Official Publication:https://doi.org/10.1186/gb-2003-4-5-r33
PubMed:View item in PubMed

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