Nicht-Vitamin-K-abhängige orale Antikoagulanzien (NOAK) bei chronischer Niereninsuffizienz [Non-vitamin K antagonist oral anticoagulants (NOAC) in chronic kidney disease]

Item Type:	Review
Title:	Nicht-Vitamin-K-abhängige orale Antikoagulanzien (NOAK) bei chronischer Niereninsuffizienz [Non-vitamin K antagonist oral anticoagulants (NOAC) in chronic kidney disease]
Creators Name:	Schlieper, G. and Remppis, A. and Schwenger, V. and Keller, T. and Dechend, R. and Massberg, S. and Baldus, S. and Weinreich, T. and Hetzel, G. and Floege, J. and Hoyer, J. and Mahfoud, F. and Fliser, D.
Abstract:	Non-vitamin K antagonist oral anticoagulants (NOAC) are administered for stroke prophylaxis in patients with atrial fibrillation and corresponding risk scores. In addition, NOAC are used for treatment and prophylaxis of venous thromboembolic events, such as deep vein thrombosis and acute pulmonary embolism and their prophylaxis in recurrent events. Clinical trials have excluded patients with advanced chronic kidney disease; therefore, data cannot always be generalized to patients with chronic kidney disease. The use of NOAC is not recommended or is contraindicated in advanced stages of chronic kidney disease.
Keywords:	Anticoagulation, Dabigatran, Rivaroxaban, Apixaban, Edoxaban
Source:	Nephrologe
ISSN:	1862-040X
Publisher:	Springer
Volume:	13
Number:	2
Page Range:	91-98
Date:	March 2018
Official Publication:	https://doi.org/10.1007/s11560-018-0230-x

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