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Approaches and techniques to characterize cancer metabolism in vitro and in vivo

Item Type:Review
Title:Approaches and techniques to characterize cancer metabolism in vitro and in vivo
Creators Name:Zaimenko, I. and Lisec, J. and Stein, U. and Brenner, W.
Abstract:Cancer metabolism is wired to sustain uncontrollable cell proliferation and ensure cell survival. Given the multitude of available approaches to study metabolic alterations it remains a challenging task to select the most appropriate method. In this mini-review we describe how cancer metabolism can be studied in vitro and in vivo providing an overview of available approaches and techniques, discussing their advantages and drawbacks and guiding through selection of an appropriate method to address particular research needs. This work is particularly intended to those cancer researchers who are new in the field but want to investigate metabolic alterations in their cancer model systems.
Keywords:Cancer Metabolism, In Vitro Techniques, In Vivo Techniques, Metabolomics, PET, MRI
Source:Biochimica et Biophysica Acta - Reviews on Cancer
Page Range:412-419
Date:December 2017
Official Publication:https://doi.org/10.1016/j.bbcan.2017.08.004
PubMed:View item in PubMed

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