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Frequency of exercise-induced ST-T-segment deviations and cardiac arrhythmias in recreational endurance athletes during a marathon race: results of the prospective observational Berlin Beat of Running study

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Item Type:Article
Title:Frequency of exercise-induced ST-T-segment deviations and cardiac arrhythmias in recreational endurance athletes during a marathon race: results of the prospective observational Berlin Beat of Running study
Creators Name:Herm, J. and Toepper, A. and Wutzler, A. and Kunze, C. and Kruell, M. and Brechtel, L. and Lock, J. and Fiebach, J.B. and Heuschmann, P.U. and Haverkamp, W. and Endres, M. and Jungehulsing, G.J. and Haeusler, K.G.
Abstract:OBJECTIVES: While regular physical exercise has many health benefits, strenuous physical exercise may have a negative impact on cardiac function. The 'Berlin Beat of Running' study focused on feasibility and diagnostic value of continuous ECG monitoring in recreational endurance athletes during a marathon race. We hypothesised that cardiac arrhythmias and especially atrial fibrillation are frequently found in a cohort of recreational endurance athletes. The main secondary hypothesis was that pathological laboratory findings in these athletes are (in part) associated with cardiac arrhythmias. DESIGN: Prospective observational cohort study including healthy volunteers. SETTING AND PARTICIPANTS: One hundred and nine experienced marathon runners wore a portable ECG recorder during a marathon race in Berlin, Germany. Athletes underwent blood tests 2-3 days prior, directly after and 1-2 days after the race. RESULTS: Overall, 108 athletes (median 48 years (IQR 45-53), 24% women) completed the marathon in 249±43 min. Blinded ECG analysis revealed abnormal findings during the marathon in 18 (16.8%) athletes. Ten (9.3%) athletes had at least one episode of non-sustained ventricular tachycardia, one of whom had atrial fibrillation; eight (7.5%) individuals showed transient ST-T-segment deviations. Abnormal ECG findings were associated with advanced age (OR 1.11 per year, 95% CI 1.01 to 1.23), while sex and cardiovascular risk profile had no impact. Directly after the race, high-sensitive troponin T was elevated in 18 (16.7%) athletes and associated with ST-T-segment deviation (OR 9.9, 95% CI 1.9 to 51.5), while age, sex and cardiovascular risk profile had no impact. CONCLUSIONS: ECG monitoring during a marathon is feasible. Abnormal ECG findings were present in every sixth athlete. Exercise-induced transient ST-T-segment deviations were associated with elevated high-sensitive troponin T (hsTnT) values. TRIAL REGISTRATION: ClinicalTrials.gov NCT01428778; Results.
Keywords:Age Factors, Arrhythmias, Cardiac, Athletes, Atrial Fibrillation, Berlin, Cardiovascular Diseases, Electrocardiography, Heart Conduction System, Monitoring, Ambulatory, Odds Ratio, Physical Endurance, Prospective Studies, Recreation, Risk Factors, Running, Troponin T
Source:BMJ Open
ISSN:2044-6055
Publisher:BMJ Publishing Group (U.K.)
Volume:7
Number:8
Page Range:e015798
Date:3 August 2017
Official Publication:https://doi.org/10.1136/bmjopen-2016-015798
PubMed:View item in PubMed

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