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A straightforward approach to N-substituted-2 H-indazol-2-amines through reductive cyclization

Item Type:Article
Title:A straightforward approach to N-substituted-2 H-indazol-2-amines through reductive cyclization
Creators Name:Schoene, J. and Bel Abed, H. and Christmann, M. and Nazare, M.
Abstract:A versatile two-step, one-pot reaction to access N-substituted-2H-indazol-2-amine derivatives has been elaborated. A diverse set of analogues was obtained by a sequential hydrazone formation and reductive cyclization in moderate to good yields from readily available starting materials. The strategy tolerates a broad range of substitutions pattern and functional groups allowing further derivatizations.
Keywords:2H-Indazole, Cadogan Reaction, N-N Bond Formation, Reductive Cyclization
Source:Tetrahedron Letters
ISSN:0040-4039
Publisher:Elsevier
Volume:58
Number:16
Page Range:1633-1635
Date:19 April 2017
Official Publication:https://doi.org/10.1016/j.tetlet.2017.03.031

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