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Keep them close: PRC2 poises enhancer-promoter interactions at anterior neuronal genes

Official URL:https://doi.org/10.1016/j.stem.2017.04.006
PubMed:View item in PubMed
Creators Name:Caglio, Giulia and Torlai Triglia, E. and Pombo, A.
Journal Title:Cell Stem Cell
Journal Abbreviation:Cell Stem Cell
Volume:20
Number:5
Page Range:573-575
Date:4 May 2017
Abstract:Enhancers exist in different epigenetic states: active, primed, or poised. However, it is not yet understood how the different enhancer states influence gene activation. In this issue of Cell Stem Cell, Cruz-Molina et al. (2017) unravel how poised enhancers activate anterior neural genes and the role of Polycomb proteins in enhancer-promoter contacts.
ISSN:1934-5909
Publisher:Cell Press (U.S.A.)
Item Type:Editorial

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